The laboratory investigates cell migration and tumor growth, with a primary focus on brain cancer progression. Using models that integrate biochemical kinetics, transport, thermodynamics, and mechanical forces, the team develops treatment strategies and has recently created a clinically-tested model for viral replication

Dr. Genin’s research focuses on interfaces between tissues at the attachment of tendon to bone, between cells in cardiac fibrosis, and between protein structures at the periphery of plant and animal cells.

Dr. Kang-Mieler’s translational, NIH-supported research projects focus on ocular drug delivery, retinal imaging and biomarkers, retinal blood flow, and electrophysiology. Her clinical interests center on retinal vascular diseases, including age-related macular degeneration and diabetic retinopathy.

Dr Presley's research efforts are focused on the development of optical-based sensors, particularly luminescent sensors for physiological monitoring.

Dr. Whalen's laboratory investigates causes and treatments for acute brain injury in children with mouse models and molecular and cell biology.

Dr. Nitin’s research integrates biomolecular engineering, mathematical modeling, material science, and molecular imaging, focusing on food engineering and biomedical engineering. The food engineering research aims to develop technologies for food safety and health initiatives, while the biomedical engineering research focuses on advancing molecular imaging technologies for early disease detection and therapeutic delivery

The Wirtz lab conducts groundbreaking research in the areas of cell motility, tumorigenesis and cancer metastasis, extracellular vesicles, digital pathology, machine learning applications to biological images, and immunology.

The Jason Burdick Biomaterials and Biofabrication Laboratory develops advanced biomaterials, such as hydrogels and biodegradable elastomers, using techniques like 3D printing and electrospinning to address medical challenges, including cardiac repair, tissue modeling, and cartilage regeneration. Their research focuses on creating cytocompatible, self-healing materials with tailored properties to meet specific biomedical needs.

The goal of Dr. Spiller's lab is to understand mechanisms by which the inflammatory response orchestrates successful tissue regeneration and to develop novel biomaterial strategies that apply these principles to situations in which regeneration is impaired.

The Stevens lab is developing tools to understand and control how nature builds tissues. It aims to create artificial human tissues and remotely control these tissues after implantation in patients. The team is working to translate its findings into new therapies for patients with heart and liver diseases.

The Maletic-Savatic lab focuses on understanding the mechanisms of adult neurogenesis and the factors that affect it, using the tools of chemistry, genetics, computational and systems neurobiology, and neuroimaging. My ultimate goal is to develop regenerative therapies, i.e., to stimulate birth and survival of new neurons in a targeted and controlled manner to enable safe treatment of a variety of disorders that affect memory and mood.

The long term goal of the June Lab is to develop novel treatment strategies for osteoarthritis. Current programs involve (1) understanding how chondrocytes and all cells respond to mechanical loads, (2) using systems biology and metabolomics to understand regulation of central metabolism, and (3) characterizing synovial fluid biomarkers to understand OA heterogeneity and move toward early diagnosis.